YD Biolabs proudly announces the launch of the Rapid 3′-End ssDNA Labeling Kit, the first commercially available solution that enables efficient, covalent modification of single-stranded DNA (ssDNA) at the 3′ end within just 1 hour. Traditionally, 3′-end labeling workflows required multi-step protocols taking several days to complete. With this breakthrough kit, researchers can now achieve high-yield, reproducible labeling in a single streamlined workflow — significantly accelerating molecular biology experiments.
Key Features
- 1-Hour Workflow — Rapidly completes 3′-end labeling compared to multi-day conventional methods.
- High Yield and Recovery — Typical recovery of 80–95% from up to 4 nmol ssDNA per reaction.
- Direct Labeling — Works with standard ssDNA without the need for modified nucleotides.
- Multiplex Compatibility — Enables simultaneous labeling of mixed oligo pools.
- NGS-Ready Applications — Optimized for hybrid-capture, target enrichment, and probe-based assays.
Applications
- NGS Target Enrichment — Efficient pull-down or capture of probe pools prior to library prep.
- Hybridization Probes — For in situ hybridization, blotting, or microarrays with minimal probe interference.
- Conjugation — Stable, oriented 3′ tagging for surfaces, antibodies, or drug conjugates.
Availability
The Rapid 3′-End ssDNA Labeling Kit is available in multiple formats, supporting a wide selection of fluorophores (FAM, VIC, TMR, Cy3, Cy5) as well as functional tags (Biotin, DBCO, Azide). Each variant is offered in 3-reaction and 10-reaction sizes to fit different experimental needs.
For more details or to place an order, please visit the Product Page or contact us at info@ydbiolabs.com
